On a GLP-1
Support for nutrition, digestion, hydration, and the everyday changes that come with a reduced appetite.
Most
people prescribed GLP-1s don't receive adequate nutrition counseling or support.
Joint advisory · ACLM, ASN, OMA, TOS · Am J Clin Nutr · 2025 · Read
Why DUO
Most people on GLP‑1s don't get nutrition support.
We built DUO to close that gap.
Your medication handles one part of the journey. DUO supports the rest, and we show our work.
The gap we're closing
The gap, in numbers.
Five findings from published research on what changes when you eat less. Each one links to the original paper.
Fluid intake1.3 L
on a GLP-1 drug vs 1.6 L on placebo (median), over an 8-hour visit
Endocrine · 2020 · RCT · Read
Studies were not conducted on DUO products. GI effects were also common with placebo in the trial.
See all researchOur mission
To support the person, not just the outcome.
When someone commits to changing their health, the change itself gets all the attention, and the day-to-day of actually living it gets none. DUO exists to make the rest of the journey easier.
Our story
Eating less doesn't mean needing less.
DUO began with our own family: people we love managing their weight, eating less, and navigating the digestive changes that came with it.
- 01
What we saw
The care focused on the medication. The day-to-day nutrition was left to guesswork.
- 02
What the research said
Years of digging showed the same pattern: smaller meals, fewer nutrients, little guidance. See the research.
- 03
What we built
A short, research-backed routine for the everyday basics. Full Supplement Facts on every product, in plain language.
11
published studies we cite and link
4
products in one simple routine
Every label
shown in full on every product page
Why "DUO"
Your journey + DUO.
Better together.
Something else is handling one part of your journey: a medication, a plan, a season of real effort. DUO handles the rest of it. Nutrition, digestion, hydration, everyday support.
That's why the mark is two overlapping circles. Two things, working together, making something neither makes alone.
YOUR JOURNEYDUO
YOUR JOURNEYDUO
Who DUO is for
Built for more than one journey.
Starting or stepping down
Build consistent nutrition, hydration and wellness habits around a changing routine.
Focused on everyday health
You don't need a GLP-1 to use DUO. The routine fits anyone eating more intentionally.
The DUO Standard
If we can't explain why it's here, it doesn't belong here.
- 01
Purposeful
Every ingredient has a clear reason to be there.
- 02
Evidence-led
Decisions informed by published research.
- 03
Transparent
Full Supplement Facts, out in the open.
- 04
Tested
Our manufacturers test for identity, potency, heavy metals and microbial contamination.
- 05
Explainable
No science degree required.
Our commitments
Our commitments.
Trust isn't a badge. It's what we show you, and what we refuse to do.
What we show you
Always
- Full Supplement Facts on every product
- The nutrition research behind DUO, linked
- The full Supplement Facts panel, for every product
- Real reviews only, unedited
What we'll never do
Never
- Paid or fake reviews
- Badges or certifications we can't prove
- “Clinically proven” claims we can't back up
- Medication brand names in our marketing
DUO products are dietary supplements, not medications.
Read the DUO StandardStart with the essential. Build around you.
Begin with DUO Daily Essential, or get all four with the Complete Routine and pay for three.
